BLM的問題，透過圖書和論文來找解法和答案更準確安心。 我們找到下列免費下載的地點或者是各式教學

The Anti-Social Contract: And Other Selected Writings

為了解決BLM的問題，作者Kly, Y. N. 這樣論述：

Dr. Y. N. Kly may be one of the most significant African American political theorists since W.E.B. DuBois. This selection of his writings seeks to encapsulate Dr. Kly’s groundbreaking presentation of the systemic situation of black Americans in the United States within the context of the norms and p

ractices of international law. It represented a paradigm shift in the understanding of African American rights, including but moving beyond the customary American view of civil rights, i.e. nondiscrimination, equality before the law, and the right to vote, to those more expansive systemic rights ela

borated in international human rights law as it concerns minorities and peoples. This publication is germane to what may be an epochal moment in American history, when the struggle for power between two mainstream American political parties, reflected in the accusations of white supremacy leveled at

the Trump presidency and the rise of the Black Lives Matter (BLM) movement, has brought the issue of African Americans’ present and historical grievances to the fore. Moreover, it is a moment when Civil Rights has been tested and not only found to be inadequate by African Americans, but is again be

ing challenged by the dominant majority and the US Supreme Court as it concerns affirmative action. It is a moment when, post the 2020 deaths of Ahmaud Arbery, Breonna Taylor and George Floyd, African Americans are flocking to their heritage institutions, the Historically Black Colleges & Universiti

es (HBCUs), seeking safety in their collectivity and freedom from the complexities of their integration into predominantly white institutions of higher learning. Dr. Kly’s work was recognized within his lifetime. Two of his books International Law and the Black Minority in the United States and A Po

pular Guide to Minority Rights won the prestigious Gustavus Myers Center for the Study of Bigotry and Human Rights Award, sponsored by major civil rights US organizations such as the NAACP, the National Bar Association and the Unitarian Universalist Church. Endorsers ranged from the American Journal

of International Law to black nationalist Kwame Ture (Stokely Carmichael) and political prisoner, Mumia Abu Jamal. He was the keynote speaker at a groundbreaking conference held at Hamline University in 1993, on the Right of African Americans to Self-Determination.

BLM進入發燒排行的影片

以建築資訊模型為基礎之醫院動線規劃系統

為了解決BLM的問題，作者徐向輝 這樣論述：

2020年世界爆發嚴重特殊傳染性肺炎(COVID-19)，截至目前(2022.01)為止全世界共有3億多人確診，雖然臺灣憑藉著增強型動線管制(enhanced Traffic Control Bundling, eTCB)理論執行清潔、隔離、檢疫與緩衝區域的動線配置以降低醫院內感染，但因目前的動線規劃需仰賴感染控制醫生以人工進行分區的規劃，且缺乏自動化的配置及分析，尚無方法驗證規劃後的動線是否影響行人流使用或造成壅塞。本研究以輔助自動規劃與驗證動線服務水準為目標，建置一動線規劃方法，可藉由電腦輔助進行分區分流規劃並模擬人流效果，提供醫院在配置動線之參考。動線規劃方法包含eTCB系統、BIM模

型、人流模擬及結果輸出四個部分。eTCB系統將使用者設定的平面房間用途，透過BIM軟體以API來分析醫院BIM模型並視覺化呈現汙染分區的規劃結果，並結合最短路徑演算法來計算房間的動線，輸出最佳的緩衝區(Intermediate)動線，以達成eTCB的防疫效果。BIM模型根據eTCB系統得出的緩衝區位置，建置動線分流的開口模型並即時看到動線規劃的結果。人流模擬將最佳緩衝區的動線進一步分析，針對輸出規劃好動線及分流的BIM模型進行動線的分析，以行人服務水準等級為標準。結果輸出以視覺化的方式呈現給感染控制醫生輔助樓層動線規劃的判斷。本研究提出的動線規劃指引結合BIM的空間視覺化與eTCB的防疫管制，

透過簡單的操作介面與行人模擬產生不同的動線規劃方案，以提升醫院動線規劃之效率及輔助，幫助疫情發生時對於醫療量能的應變能力，並落實汙染分區及動線分流規劃。透過案例的導入與分析，發現動線分流模型搭配動線開口，可再維持原先的動線服務水準下增進動線的流速與降低染疫的風險。

Weapons of Mass Delusion: How the Republican Party Lost Its Mind

為了解決BLM的問題，作者Draper, Robert 這樣論述：

The disturbing eyewitness account of how a new generation of Republicans--led by Marjorie Taylor Greene, Paul Gosar, Matt Gaetz, Lauren Boebert, and Madison Cawthorn--far from moving on from Trump, have taken the politics of hysteria to even greater extremes, bringing American democracy to the very

edge of reasonThe violent insurrection at the US Capitol on January 6th, 2021 was a terrible day for American democracy, but at least, many people dared hope that, after it was over, the fever would then be broken, Trump’s absurd and relentless set of lies about the stealing of the 2020 election mad

e unspeakable. That is not what happened. Instead, shockingly, ＂the big steal＂ has increasingly become dogma among an ever-higher percentage of American Republicans. What happened to the Republican Party, and America, during the Trump presidency is a story we more or less think we know. What has hap

pened to the party since, it turns out, is even more disturbing. That is the story Robert Draper tells here. Through his extraordinarily intrepid reporting on the ground across the country, Draper chronicles the road from January 6th to the 2022 midterms among the Republican base and in the US Cong

ress, as Marjorie Taylor Greene and her ilk have come to shape their party’s terms of engagement to an extent that would have been unimaginable even ten years ago. He brings to life the efforts of a dwindling group of Republicans who are willing to push back against the falsehoods, in the face of a

group of ascendent demagogues who are merrily weaponizing them. With a base whipped up into a perpetual frenzy of outrage by conspiracy theories--not just about the big steal, but about COVID and vaccines, Antifa and BLM and George Soros and the Rothschilds and President Obama and on and on and on--

the forces of reason within the GOP are on the defensive, to put it mildly. The leadership of the anti-Trump resistance among Republicans in Congress has cooperated extensively with the author; the book also benefits greatly from reporting conducted in Texas, Arizona, Georgia, Florida, and other bel

lwether states in the country of the mind one might call Conspiracyland. Robert Draper has been a wise, fearless, and fair-minded chronicler of the American political scene for over 25 years. He has seen the good, the bad, and the ugly. He has never seen it this ugly. Ultimately, this book tells th

e story of a fearful test of our ability, as a country, to hold together a system of government grounded in truth and the rule of law. It’s difficult to imagine a book that could underscore the stakes of the 2022 midterm elections more powerfully. Robert Draper is a writer at large for the New Yo

rk Times Magazine and a contributing writer for National Geographic Magazine. He is the author of several books, including the New York Times bestseller, Dead Certain: The Presidency of George W. Bush. He lives in Washington D.C. with his fiancee, Kirsten Powers.

探討 hnRNPK 與 DDX3 蛋白的相互作用促進去氧核醣核酸損傷所引起的細胞凋亡之機制

為了解決BLM的問題，作者陳喬哲 這樣論述：

異質核醣核酸蛋白 K (Heterogeneous nuclear ribonucleoprotein K; hnRNPK) 是一種核糖核酸/去氧核醣核酸結合蛋白，藉由其功能域和特定 DNA、RNA 與蛋白質結合，一同參與調控細胞生理反應，除此之外，hnRNPK 蛋白上的轉譯後修飾也會影響其功能。目前已知 hnRNPK 在癌症的轉型、轉移以及進程上扮演著協助的角色、不過 hnRNPK 調控癌症惡化的詳細機制目前仍不清楚。另一方面，hnRNPK 也可以和 p53 共同調控去氧核醣核酸損傷所引起的細胞凋亡，根據實驗室先前的研究得知，hnRNPK 上的兩個精胺酸 296/299 具有甲基化修飾時會

干擾 PKCδ 調控鄰近的絲胺酸 302 磷酸化反應，進而抑制 U2OS 細胞因去氧核醣核酸損傷所引起的細胞凋亡，相反的精氨酸 296/299 無法甲基化的hnRNPK突變株 (hnRNPKMD) 則會促進細胞凋亡。本篇研究發現在去氧核醣核酸損傷的情況下，有一種 DEAD 盒 (DEAD-box) 核醣核酸解螺旋酶 DDX3 能和 hnRNPKMD 結合並增強 hnRNPKMD 所調控的細胞凋亡，而且實驗證實 DDX3 是透過羧基端和 hnRNPK 結合，因此截斷DDX3 的羧基端後可觀察到其無法和 hnRNPK 結合而失去促進細胞凋亡的能力。值得注意的是，實驗結果顯示一種結合在 DDX3 三

磷酸腺苷結合位的 DDX3 抑制劑 RK-33，反而能促進 DDX3 和 hnRNPK 的結合進而造成更強的細胞凋亡反應。不過在etoposide藥物 處理後，原先因去氧核醣核酸損傷所引起的 p53 蛋白表現反而會受到 RK-33 抑制。綜合以上結果發現，當 U2OS 細胞產生去氧核醣核酸損傷時，可以透過 hnRNPK 和 DDX3 交互作用但不需要p53的方式促進細胞凋亡，未來也許可以利用此交互作用作為促進細胞凋亡的標靶來製定對抗癌症的策略。